Diabetes gestacional e os efeitos do exercício físico em sua prevenção
Resumo
O diabetes mellitus gestacional (DMG) é uma das complicações mais frequentes da gravidez e o exercício físico é uma proposta para prevenção. O objetivo desta revisão sistemática consiste em sintetizar os estudos randomizados controlados de programas de exercícios físicos, durante a gravidez para e apresentar seus efeitos acerca da prevenção da DMG e seus benefícios. Esta revisão teve como fonte de pesquisa os bancos de dados bibliográficos da Cochrane Library Plus, Wholis, Scielo, PubMed e Web of Science. A estratégia de busca aplicada foi à pesquisa por termos como “gravidez ou gestação”, “exercício físico ou atividade física na gestação”, “diabetes gestacional ou resistência à insulina” e “ganho de peso materno ou ganho de peso gestacional”. Foram recuperadas 665 referências, dos quais 10 deles atendiam aos critérios de inclusão e foram usadas para análise. O estudo verificou que o exercício físico durante a gravidez impede o ganho excessivo de peso materno reduzindo o risco de DMG, sem apresentar risco para o bem-estar materno e fetal. Os benefícios dos programas são maiores quando a intervenção inclui exercícios combinados. Dessa forma mulheres sem contraindicações obstétricas devem ser encorajadas a realizar exercícios físicos com o devido acompanhamento e orientações.
Referências
American College of Obstetricians and Gynecologists (2020). Physical activity and exercise during pregnancy and the postpartum period: ACOG Committee Opinion Nr. 804. American College of Obstetricians and Gynecologists. Obstetrics and Gynecology, 1354), e178-e188. https://doi.org/10.1097/aog.0000000000003772
American Diabetes Association (2018). 5. Prevention or delay of type 2 diabetes: standards of medical care in diabetes. Diabetes Care, 41(Supplement 1), S51-S54. https://doi.org/10.2337/dc18-S005
Bacchi, M., Mottola, M., Perales, M., Refoyo, I., e Barakat, R. (2017). Aquatic activities during pregnancy prevent excessive maternal weight gain and preserve birth weight. A randomized clinical trial. American Journal of Health Promotion, 32(3), 729-735. https://doi.org/10.1177/0890117117697520
Bain, E., Crane, M., Tieu, J., Han, S., Crowther, C.A., e Middleton, P. (2015). Diet and exercise interventions for preventing gestational diabetes mellitus. Cochrane database of Systematic Reviews, (4). CD010443. https://doi.org/10.1002/14651858.CD010443.pub2
Barakat, R., Cordero, Y., Coteron, J., Luaces, M., e Montejo, R. (2012). Exercise during pregnancy improves maternal glucose screen at 24-28 weeks: a randomized controlled trial. British Journal of Sports Medicine, 46, 656-661. http://dx.doi.org/10.1136/bjsports-2011-090009
Barakat, R., Pelaez, M., Lopez, C., Lucia, A., e Ruiz, J. R. (2013). Exercise during pregnancy and gestational diabetes-related adverse effects: a randomised controlled trial. British Journal of Sports Medicine, 47, 630-636. http://dx.doi.org/10.1136/bjsports-2012-091788
Barakat, R., Perales, M., Bacchi, M., Coteron, J., e Refoyo, I. (2014). A program of exercise throughout pregnancy. Is it safe to mother and newborn? American Journal of Health Promotion, 29(1), 2–8. https://doi.org/10.4278/ajhp.130131-QUAN-56
Barakat, R., Perales, M., Cordero, Y., Bacchi, M., e Mottola, M.F. (2017). Influence of Land or Water Exercise in Pregnancy on Outcomes: A Cross-sectional Study. Medicine and science in sports and exercise, 49(7), 1397-1403. https://doi.org/10.1249/mss.0000000000001234
Barakat, R., Refoyo, I., Coteron, J., e Franco, E. (2019). Exercise during pregnancy has a preventative effect on excessive maternal weight gain and gestational diabetes. A randomized controlled trial. Brazilian journal of physical therapy, 23(2), 148-155. https://doi.org/10.1016/j.bjpt.2018.11.005
Cavalcante, S.R., Cecatti, J.G., Pereira, R.I., Baciuk, E.P. Bernardo, A.L., e Silveira, C. (2009). Water aerobics II: maternal body composition and perinatal outcomes after a program for low risk pregnant women. Reproductive Health, 6(1). https://doi.org/10.1186/1742-4755-6-1
Cid, M., e González, M. (2016). Potential benefits of physical activity during pregnancy for the reduction of gestational diabetes prevalence and oxidative stress. Early human development, 94, 57-62. https://doi.org/10.1016/j.earlhumdev.2016.01.007
Cordero, Y., Mottola, M.F., Vargas, J., Blanco, M., e Barakat, R. (2015). Exercise is associated with a reduction in gestational diabetes mellitus. Medicine and Science in Sports and Exercise, 47(7), 1328-1333. https://doi.org/10.1016/j.earlhumdev.2016.01.007
da Silva, SG, Hallal, PC, Domingues, MR, Bertoldi, AD, da Silveira, MF, Bassani, D., da Silva, ICM, da Silva, BGC, Coll, CVN, e Evenson, K. (2017). A randomized controlled trial of exercise during pregnancy on maternal and neonatal outcomes: results from the PAMELA study. International Journal of Behavioral Nutrition and Physical Activity, 14(1), 1-11. https://doi.org/10.1186/s12966-017-0632-6
Davenport, MH, Sobierajski, F., Mottola, MF, Skow, RJ, Meah, VL, Poitras, VJ, Gray, CE, Garcia, AJ, Barrowman, N., Riske, L., James, M., Nagpal, TS, Marchand, AA, Slater, LG, Adamo, KB, Davies, GA, Barakat, R., e Ruchat, SM (2018). Glucose responses to acute and chronic exercise during pregnancy: a systematic review and meta-analysis. British journal of sports medicine, 52(21), 1357-1366. https://doi.org/10.1136/bjsports-2018-099829
Davenport, M., Skow, R.J., e Steinback, C.D. (2016). Maternal responses to aerobic exercise in pregnancy. Clinical Obstetrics and Gynecology, 59(3), 541-551. http://dx.doi.org/10.1136/bjsports-2018-099829
Doi, S.A., Furuya-Kanamori, L., Toft, E., Musa, O.A., Mohamed, A.M., Clark, J., e Thalib, L. (2020). Physical activity in pregnancy prevents gestational diabetes: A meta-analysis. Diabetes Research and Clinical Practice, 168, 108371. https://doi.org/10.1016/j.diabres.2020.108371
Ehrlich, SF, Sternfeld, B., Krefman, AE, Hedderson, MM, Brown, SD, Mevi, A., Chasan-Taber, L., Quesenberry Jr., CP, e Ferrara, A. (2016). Moderate and vigorous intensity exercise during pregnancy and gestational weight gain in women with gestational diabetes. Maternal and child health journal, 20(6), 1247-1257. https://doi.org/10.1007/s10995-016-1926-z
Galliano, L.M., Del Vecchio, A.H., Silvani, J., Façanha, C., e Del Vecchio, F.B. (2019). Physical activity level in women with gestational diabetes mellitus: Lifestyle INtervention for Diabetes prevention After pregnancy (LINDA‐Brasil) study. Journal of diabetes, 11(6), 457-465. https://doi.org/10.1111/1753-0407.12872
Garnaes, K.K., Morkved, S., Salvesen, O., e Moholdt, T. (2016). Physical training and weight gain in obese pregnant women: a randomized controlled trial (ETIP study). Public Library of Science Medicine, 13(7), e1002079. https://doi.org/10.1371/journal.pmed.1002079
Gilinsky, A.S., Kirk, A.F., Hughes, A.R., e Lindsay, R.S. (2015). Lifestyle interventions for type 2 diabetes prevention in women with prior gestational diabetes: A systematic review and meta-analysis of behavioural, anthropometric and metabolic outcomes. Preventive Medicine Reports, 2, 448-461. https://doi.org/10.1016/j.pmedr.2015.05.009
Hod, M., Kapur, A., Sacks, DA, Hadar, E., Agarwal, M., Di Renzo, GC, Roura, LC, McIntyre, HD, Morris, JL, e Divakar, H. (2015). The International Federation of Gynecology and Obstetrics (FIGO) Initiative on gestational diabetes mellitus: A pragmatic guide for diagnosis, management, and care. International Journal of Gynecology & Obstetrics, 131, S173-S211. https://doi.org/10.1016/S0020-7292(15)30033-3
Hopkins, S., Baldi, J.C., Cutfield, W.S., McCowa, L., e Hofman, P.L. (2010). Effects of exercise training on maternal hormonal changes in pregnancy. Clinical Endocrinology, 74(4), 495-500. https://doi.org/10.1111/j.1365-2265.2010.03964
International Diabetes Federation (2017). IDF Diabetes Atlas Eighth edition 2017. International Diabetes Federation. https://diabetesatlas.org/upload/resources/previous/files/8/IDF_DA_8e-EN-final.pdf
May, L.E., Allen, J.J., e Gustafson, K.M. (2016). Fetal and maternal cardiac responses to physical activity and exercise during pregnancy. Early human development, 94, 49-52. https://doi.org/10.1016/j.earlhumdev.2016.01.005
Ming, WK, Ding, W., Zhang, CJP, Zhong, L., Long, Y., Li, Z., Sun, C., Wu, Y, Chen, H., Chen, H., e Wang, Z. (2018). The effect of exercise during pregnancy on gestational diabetes mellitus in normal-weight women: a systematic review and meta-analysis. BMC pregnancy and childbirth, 18(1), 1-9. https://doi.org/10.1186/s12884-018-2068-7
Mottola, MF, Davenport, MH, Ruchat, SM, Davies, GA, Poitras, VJ, Gray, CE, Garcia, AJ, Barrowman, N., Adamo, KB, Duggan, M., Barakat, R., Chilibeck, P., Fleming, K., Forte, M., Korolnek, J., Nagpal, T., Slater, LG, Stirling, D., e Zehr, L. (2018). 2019 Canadian guideline for physical activity throughout pregnancy. British Journal of Sports Medicine, 52(21), 1339-1346. http://dx.doi.org/10.1136/bjsports-2018-100056
Nasiri-Amiri, F., Bakhtiari, A., Faramarzi, M., Rad, H.A., e Pasha, H. (2016). The association between physical activity during pregnancy and gestational diabetes mellitus: a case-control study. International journal of endocrinology and metabolism, 14(3). https://doi.org/10.5812/ijem.37123
Organização Pan-Americana da Saúde (2016). Rastreamento e diagnóstico de diabetes mellitus gestacional no Brasil. Ministério da Saúde. Federação Brasileira das Associações de Ginecologia e Obstetrícia. Sociedade Brasileira de Diabetes https://www.diabetes.org.br/profissionais/images/pdf/diabetes-gestacional-relatorio.pdf
Price, B.B., Saeid, B., e Kappeper, K. (2012). Exercise in pregnancy: effect on fitness and obstetric outcomes‐A randomized trial. Medicine & Science in Sports & Exercise, 44(12), 2263-2269. https://doi.org/10.1249/MSS.0b013e318267ad67
Sanabria‐Martínez, G., García‐Hermoso, A., Poyatos‐León, R., Álvarez‐Bueno, C., Sánchez‐López, M., e Martínez‐Vizcaíno, V. (2015). Effectiveness of physical activity interventions on preventing gestational diabetes mellitus and excessive maternal weight gain: a meta‐analysis. BJOG: An International Journal of Obstetrics & Gynaecology, 122(9), 1167-1174. https://doi.org/10.1111/1471-0528.13429
Shepherd, E., Gomersall, J. C., Tieu, J., Han, S., Crowther, C. A., e Middleton, P. (2017). Combined diet and exercise interventions for preventing gestational diabetes mellitus. Cochrane Database of Systematic Reviews, (11). https://doi.org/10.1002/14651858.CD010443.pub3
Sociedade Brasileira de Diabetes (2019). Diretrizes da Sociedade Brasileira de Diabetes 2019-2020. Editora Clannad. https://www.diabetes.org.br/profissionais/images/DIRETRIZES-COMPLETA-2019-2020.pdf
Tomic, V., Sporis, G., Tomic, J., Milanovic, Z., Zigmundovac‐Klaic, D., e Pantelic, S. (2013). The effect of maternal exercise during pregnancy on abnormal fetal growth. Croatian Medical Jornal, 54(4), 362-368. https://doi.org/10.3325/cmj.2013.54.362
Trujillo, J., Vigo, A., Reichelt, A., Duncan, B.B., e Schmidt, M.I. (2014). Fasting plasma glucose to avoid a full OGTT in the diagnosis of gestational diabetes. Diabetes research and clinical practice, 105(3), 322-326. https://doi.org/10.1016/j.diabres.2014.06.001
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